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KNOWLEDGE DOMAINS AND USEFUL LINKS

 

General

Chief Scientist Office (CSO): www.sehd.scot.nhs.uk/cso
This website explains the process in which Clinical Trials seek ethical approval.

 

NHS trials: www.library.nhs.uk/trials
This website provides general information about clinical trials, about how they are run and what to expect if you take part. There are further links to more detailed registers of specific trials.

 

Medical Research Council: www.ctu.mrc.ac.uk/trialinfo.asp
The Clinical Trials Unit of the Medical Research Council specialises in trials in HIV/AIDS and cancer, but also runs trials in other areas such as arthritis and respiratory diseases.

 

UK Clinical Research Network: www.ukcrn.org.uk
The UK Clinical Research Network was established to support clinical research and to facilitate the conduct of trials and other well-designed studies across the UK. The search facility http://public.ukcrn.org.uk/search lists studies across the UK in a wide range of medical conditions. Although the information listed is more suited to a professional audience there is also a user guide on how to use the search facility and a number of articles for the public on getting involved in clinical trials.

 

Database of current trials: www.controlled-trials.com/mrct
The Current Controlled Trials website is published by a medical publishing company, Current Controlled Trials Ltd and lists information about randomised controlled trials across the world. The information is geared more to health professionals than the general public.

 

Drug company trials: www.ifpma.org/clinicaltrials
The International Federation of Pharmaceutical Manufacturers & Associations is a global non-profit organisation representing the pharmaceutical, biotech and vaccine manufacturing industries. The clinical trials database is world-wide so searches can return large numbers of hits. The information is also more suited to health professionals than the general public.

 

Clinical Trials Registry: www.clinicaltrials.gov
ClinicalTrials.gov is a service of the United States National Institutes of Health. It lists information on over 60,000 trials sponsored by the National Institutes of Health, other federal agencies and private industry and includes trials run around the world.

Cancer-related

Cancer Research UK: www.cancerhelp.org.uk/trials/trials
CancerHelp UK is the patient information website of Cancer Research UK. This excellent web site has information written specifically for the public and the clinical trials listings are also easy to use and understand. There are currently over 300 UK trial listed.

 

Cancerbackup: www.cancerbackup.org.uk/Treatments/Trials/Search
Cancerbackup, now merged with MacMillan Cancer Support is another major UK charity providing reliable information on cancer. The search engine looks at UK trials (usually also listed on CancerHelp UK) but also cancer research trials in Europe.

 

The National Cancer Research Network: www.ncrn.org.uk
The National Cancer Research Network (NCRN) provides the NHS with the infrastructure to support cancer clinical trials in England. The website provides information about NCRN and includes resources and useful links for health professionals and the public. Contact details for cancer–related Clinical Trials Units across the UK are listed.

 

National Cancer Institute: www.cancer.gov/clinicaltrials
This is the cancer-specific equivalent of ClinicalTrials.gov. Although US-based it lists cancer trials going on around the world.

Other information

People in Research: www.peopleinresearch.org
People in Research is a UK Clinical Research Collaboration project that has been led by one of its Partner organisations, INVOLVE. Its purpose is to help members of the public make contact with organisations that want to actively involve them in clinical research. For example this could be by helping to decide what gets researched or possibly helping to carry out part of the research.

 

INVOLVE: www.invo.org.uk
INVOLVE is a national advisory group that is funded by the National Institute for Health Research. It was established to promote and support active public involvement in NHS, public health and social care research in order to improve the way that research is prioritised, commissioned, undertaken, communicated and used.

 

MRUK Survey May 2010: MRUK Survey May 2010
1,040 adults in Scotland were asked whether they agreed or disagreed with the following statement: “The NHS has a duty to determine the safety and effectiveness of the drugs its doctors prescribe”. Almost all of the respondents (97%) agreed with the statement. The question was asked as part of the CELLO mruk Scottish Consumer Omnibus Survey in May 2010.

 

Understanding Clinical Trials booklet: 
www.ukcrc.org/pdf/CT leaflet for web.pdf
A booklet giving basic details on clinical trials, produced by the Association of Medical Research Charities.

 

Clinical trials for medicinal products:
The Medicines and Healthcare products Regulatory Agency (MHRA), which is an executive agency of the Department of Health, is the statutory body in the UK responsible for ensuring that medicines and medical devices work and are acceptably safe.

 

Information on how clinical trials on medicinal products are conducted is at:
www.mhra.gov.uk/Howweregulate/Medicines/Licensingofmedicines/Clinicaltrials

 

 

 

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